ag娱乐网址登录

> 资讯 > 疾病要闻 > 正文

睡不好真的会变傻,你离痴呆还远吗?

2020-10-02 00:00:00梅斯医学
核心提示:“阿尔茨海默病”最早由德国医生阿尔茨海默(Alzheimer)在1906年发现,俗称老年痴呆症,简称AD。AD是老年期痴呆中最常见的病理类型。早期以明显记忆下降为主,逐渐丧失日常生活能力,并伴有精神症状和行为障碍,病情呈进行性进展,晚期常出现吞咽困难,卧床不起,发病十年左右,常因感染等并发症死亡。

  “AERCIHAIMOBING”ZUIZAOYOUDEGUOYISHENGAERCIHAIMO(Alzheimer)ZAI1906NIANFAXIAN,SUCHENGLAONIANCHIDAIZHENG,JIANCHENGAD。ADSHILAONIANQICHIDAIZHONGZUICHANGJIANDEBINGLILEIXING。ZAOQIYIMINGXIANJIYIXIAJIANGWEIZHU,ZHUJIANSANGSHIRICHANGSHENGHUONENGLI,BINGBANYOUJINGSHENZHENGZHUANGHEXINGWEIZHANGAI,BINGQINGCHENGJINXINGXINGJINZHAN,WANQICHANGCHUXIANTUNYANKUNNAN,WOCHUANGBUQI,FABINGSHINIANZUOYOU,CHANGYINGANRANDENGBINGFAZHENGSIWANG。

  GENJUGUOJIAERCIHAIMOBINGXIEHUIFABUDEBAOGAOXIANSHI,2018NIANQUANQIULAONIANCHIDAIHUANZHEYUEWEI5000WAN,PINGJUNMEI3MIAOZHONGJIUYOUYIWEILAORENBEIZHENDUANWEILAONIANQICHIDAI。2017NIANZHONGGUOJINGSHENJIBINGLIUXINGBINGXUEDIAOCHAXIANSHI,WOGUO65SUIJIYISHANGRENQUNLAONIANQICHIDAIHUANBINGLVWEI5.56%,JUCITUISUAN,ZHONGGUOYOUYUEYOU1000WANLAONIANRENLIHUANLAONIANCHIDAI,CHENGWEIQUANQIUCHIDAIRENSHUZUIDUODEGUOJIA。

  NEIME,XIANGZHIDAOZIJISHENMESHIHOUHUIDELAONIANCHIDAIME?XIANGZHIDAOZENMEYOUXIAOYUFANGLAONIANCHIDAIME?MEIGUOJIAZHOUDAXUEBOKELIFENXIAOZHUANJIAKAIZHANDEYIXIANGZUIXINYANJIUBIAOMING,ZHENDUIZHEIZHONGMUQIANSHANGWUYOUXIAOLIAOFADEZHIMINGJIBING,ZUIFANGBIANYOUXIAODEYUFANGCUOSHIJIUSHIJINXINGDALIANGSHENDUSHUIMIAN。

  JIWANGDEQUANWEIYANJIUYIJINGFAXIAN,ADHUANZHENAONEIDOUYOULIANGZHONGBIAOZHIXINGDANBAIZHI——βDIANFENYANGDANBAI(Aβ)HEtauDANBAIDELEIJI。QIZHONG,AβBEIRENWEIYUXUEXIYIJIDANAODESHIYINGNENGLIYOUGUAN,ERtauDANBAIZHUYAODIAOJIESHENJINGYUANXIBAOZHIJIANDEZHENGCHANGXINHAOCHUANDAO。CIWAI,LAIZIMEIGUOHAFODAXUEDEZHUANJIATUANDUICENGBAODAO,MANBOSHUIMIANPOHUAIHUIDAOZHINAONEIAβSHUIPINGSHENGGAOYUE30%,ERJINYIWANSHANGSHUIMIANBUZUJIKEDAOZHINAOJIYEZHONGtauHANLIANGZENGJIADUODA50%。

  JIAZHOUDAXUEBOKELIFENXIAODESHENJINGKEXUEJIAMatthew WalkerHEJoseph WinerJIAOSHOUWEICIZHAODAOLEYIZHONGFANGFA,KEYIZAIMOUZHONGCHENGDUSHANGZHUNQUEDIGUJIYIGERENYISHENGZHONGZUIKENENGFASHENGADDESHIJIANFANWEI。WalkerJIAOSHOUSHUO:“WOMENXIANZAIDESHUIMIANJIHUJIUXIANGYIGESHUIJINGQIU,GAOSUWOMENCHIDAIDEFABINGSHIJIANHEFAZHANSUDU。”GAIYANJIUJIEGUOYU9YUE3RIFABIAOZAI《DANGDAISHENGWUXUE》(Current Biology)ZAZHISHANG。

  XIANQIANZAIJIANKANGDONGWUHERENLEIZHONGJINXINGDEYANJIUBIAOMING,YIZHENGYEDESHUIMIANBODUOHOU,AβDENAONEIHANLIANGJIAOGAO。YINCIYANJIURENYUANJIASHE,SHUIMIANJIEGOUHESHENGLIGONGNENG(RUFEIKUAISUDONGYANSHUIMIAN(NREM)MANBOHUODONG,SHENDUSHUIMIANJIEDUAN)KEYIZUOWEIYUCEAβSUISHIJIANLEIJISUDUDEQIANZHANXINGBIAOZHIWU。

  YANJIUNARU32MINGLINCHUANGBIAOXIANZHENGCHANGDECHENGNIANREN,SHIYONGDUODAOSHUIMIANYIJIHEPETSAOMIAODUIAβJILEICHENGDUJINXINGZONGXIANGZHUIZONG。JIEGUOFAXIAN,<1HZDENREM MANBOHUODONGBILIHESHUIMIANXIAOLV(ZONGSHUIMIANLIANGZHANZONGWOCHUANGSHIJIANDEBAIFENBI)DOUKEYIYUCEAβSUISHIJIANDECHENJISUDU,QIEZAIXIAOZHENGQITAXIANGGUANYINSUHOU,CIXIANGGUANXINGRENGRANCUNZAI。JI,ZAIYANJIUGUOCHENGZHONG,LINGSANSHUIMIANDUOERNREMMANBOSHUIMIANSHAODERENAβNAONEICHENJIGENGDUO、GENGKUAI。

  WinerJIAOSHOUSHUO:“ZHEIYIYANJIUJILEWOMENYIXIANXIWANG,JIUSHIWOMENKEYIZUOYIXIESHIQINGLAIYUFANGLAONIANCHIDAI。WOMENWUXUKANZHEHUANZHEYIBUBUXIANGADJINZHANQIESHOUZUWUCUO,ERSHIXIANZAIJIUTONGGUOPINGGUSHUIMIANZHILIANGLAIYUCEAβHANLIANGDEBIANHUA。SUIZHESHIJIANDELIUSHI,HOUZHEZAIDANAOZHONGDELEIJISUDUJIUNENGZAIYIDINGCHENGDUSHANGQUEDINGLAONIANCHIDAIFASHENGDESHIJIAN”。

  JINGUANZHIQIANDEYANJIUFAXIAN,SHUIMIANKEYIDUIDANAOZHONGDEAβDANBAICHENJIJINXING“QINGJIE”,DANGAIYANJIUJINYIBUQUEDINGLESHENDUFEIKUAISUDONGYANMANBOSHUIMIANZUOWEIRENZHIGONGNENGXIAJIANGDEGANYUMUBIAO。CIWAI,MUQIANDEJIYINJIANCEKEYIYIDINGCHENGDUSHANGYUCELIHUANADDEMINGANXING、XUEYEJIANCEYEKEYITIGONGZHENDUANYIJU,DANTAMENDOUBUNENGXIANGSHUIMIANYIYANGTONGGUODUISHENGHUOFANGSHIJINXINGGANYUYITIGONGZHILIAODEQIANLI。

  YOUYULAONIANCHIDAIFASHENGLIANGGEHEXINYINSU——NAOZHONGtauHEAβDANBAIDEJILEIZAITEZHENGXINGJIYIZHANGAICHUXIANZHIQIANHENJIUJIUKENENGCHUXIAN,YINCIGAITUANDUIZAOJIUZHENDUISHUIMIANYULAONIANCHIDAIGUANXIJINXINGLEYANJIU。2019NIANZAI《SHENJINGKEXUEZAZHI》(The Journal of Neuroscience)SHANGTICHU,SHUIMIANSHINAONEItauHEAβDANBAIXUJIDEGUANJIAN。YANJIURENYUANJIEHELEAβHEtauDEPETSAOMIAO,NAODIANTUJILUSHUIMIANBINGJIEHEZIWOFANKUISHUIMIANQINGKUANGYIPINGGUSHUIMIANZAIYUCELAONIANRENADBINGLIFAZHANFANGMIANDEQIANZAIZUOYONG。HUIGUIFENXIBIAOMING,MANSUZHENDANG-SHUIMIANFANGCHUITISHOUSUNDEYANZHONGCHENGDUYUSHIZHENEICENIEYEFUHEZENGJIA,QIEAβJILEIKEYUCE<1HzMANBOHUODONGJIANSHAODEFUDU。CIWAI,BINGLIXUEHEZIWOFANKUISHUIMIANSHIZHANGZHIJIANDEGUANXIBIAOMING,ZHENGGESHENGMINGZHOUQIDESHUIMIANBIANHUAQUSHIKEYIYUCEWANNIANNAONEIAβHEtauDANBAIFUDAN。

  WalkerJIAOSHOURENWEI,CHIXUYANJIUSHUIMIANYULAONIANCHIDAIZHIJIANDEGUANXIZAIADDEFENZIHEXIBAOSHENGWUXUEFANGMIANJUYOUGUANGKUODEQIANJING。TABUJINJUYOUYUFANGADDEQIANLI,ERQIEHAIYOUWANGGAISHANJINGSHENJIBINGHEXINCHENDAIXIEJIBINGDEZHENDUANHEZHILIAO。JIEXIALAI,YANJIURENYUANJIANGMIAOZHUNJUYOULAONIANCHIDAIGAOFENGXIANDEHUANZHE,TANSUOZHAODAOGAISHANSHUIMIANDEGANYUFANGFA,YIYANHUANSHENZHIBIMIANCHIDAIDEFASHENG。

  SUIRANSHUIMIANDUIYUFANGLAONIANCHIDAIJUYOUZHONGYAOZUOYONG,DANYINGBIKAIYIGEWUQU——JI,SHUIMIANSHIJIANYUEZHANGYUEHAO(CIQIANWOMENDEWENZHANG《JINRITEKAN:SHUIMA》JIUBAODAO,SHUIMIANGUODUOHUIZENGJIAGUANXINBINGHEZUZHONGFENGXIAN)。JIUCI,FUDANDAXUEFUSHUHUASHANYIYUANSHENJINGNEIKEYUJINTAIJIAOSHOUTUANDUIZHENDUIJINQIANREN、LISHI3NIANDEDUILIEYANJIUFAXIAN:BAITIANJINGCHANGFANKUNERYEJIANSHUIMIANBUZUHUOGUODUODERENCHIDAIFENGXIANZENGJIA。XIANGFAN,MEIWAN22DIANSHUIJUE,SHUIMIANSHIZHANGDAYUEZAI6-7XIAOSHIKEMINGXIANJIANGDIGAIRENZHIZHANGAIFENGXIAN。GAIJIEGUOFABIAOZAIQUANWEIQIKAN《AERCIHAIMOBINGYUCHIDAI》 (Alzheimer&#ag娱乐网址登录;s & Dementia)ZAZHISHANG。

  GAIYANJIUSHOUCICONGSHENGWUBIAOZHIWUCENGMIANZHENGSHILEZAIZHONGLAONIANRENQUNZHONG,YEJIANSHUIMIANSHIJIANYULAONIANCHIDAIBINGLIFASHENGZHIJIANDEUXINGGUANXI。TONGSHI,YUJIAOSHOUTUANDUIHAIJINYIBUHUIZHILESHUIMIANYURENZHIZHANGAI(BAOKUOAD)FENGXIANZHIJIANGUANLIANDEZHENGJUTIXI,JIEGUOFAXIAN10ZHONGSHUIMIANTEZHENGKECUJINRENZHIZHANGAIFASHENG,QIZHONG6ZHONGYOUZHONGDENGQIANGDUYISHANGZHENGJUZHICHENG,BAOKUOSHIMIAN、SHUIMIANDUANXU、RUSHUIKUNNAN、KUAISUYANDONGSHUIMIANZHANGAI、RIJIANGONGNENGZHANGAIYIJIZAICHUANGSHANGSHIJIANGUODUO。

  ZONGZHI,SHANGSHUYANJIUBIAOMING,SHUIMIANJIANCESHIYUCELAONIANCHIDAIJIBINGJINZHANDEFEIQINRUXINGTIDAIFANGFA。SHUIMIANZHILIANGPINGGUYOUZHUYUWOMENZHUNQUEGUJICHIDAIGUANJIANDANBAIDEJILEIQINGKUANG。ERZUIJIADESHUIMIANMOSHIKEYUFANGCHIDAIDEFASHENG。XIWANGZAIBUJIUDEJIANGLAI,KEXUEJIAMENNENGZHAODAOTIGAOSHUIMIANZHILIANGDEYOUXIAOFANGFA。

特别策划
热门问答
健康视频
2019-05-15
2019-04-29
2019-04-12
2019-04-12
var _hmt = _hmt || []; (function() { var hm = document.createElement("script"); hm.src = "https://hm.baidu.com/hm.js?78ebdacae9da971faf025645ab77d367"; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(hm, s); })();